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Finding ATF4/p75NTR/IL-8 Signal Pathway in Endothelial–Mesenchymal Transition by Safrole Oxide

Targeting the endothelial-to-mesenchymal transition (EndoMT) may be a novel therapeutic strategy for cancer and various diseases induced by fibrosis. We aimed to identify a small chemical molecule as an inducer of EndoMT and find a new signal pathway by using the inducer. Safrole oxide (SFO), 50 µg/...

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Detalles Bibliográficos
Autores principales: Ge, Di, Jing, Qingchuan, Zhao, Wenbo, Yue, Hongwei, Su, Le, Zhang, ShangLi, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048316/
https://www.ncbi.nlm.nih.gov/pubmed/24905361
http://dx.doi.org/10.1371/journal.pone.0099378