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Interleukin-35 Induces Regulatory B Cells that Suppress CNS Autoimmune Disease
Interleukin 10-producing regulatory B-cells (Breg-cells) suppress autoimmune diseases while aberrant elevation of Breg-cells prevents sterilizing immunity, promotes carcinogenesis and cancer metastasis by converting resting CD4(+) T-cells to regulatory T-cells (Tregs). It is therefore of interest to...
Autores principales: | Wang, Ren-Xi, Yu, Cheng-Rong, Dambuza, Ivy M., Mahdi, Rashid M., Dolinska, Monika, Sergeey, Yuri V., Wingfield, Paul T., Kim, Sung-Hye, Egwuagu, Charles E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048323/ https://www.ncbi.nlm.nih.gov/pubmed/24743305 http://dx.doi.org/10.1038/nm.3554 |
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