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Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication

Objective: Peptic ulcer disease in children is rare. Therefore, the diagnosis can be missed until complications such as perforation or hemorrhage occur. Few reports have investigated the procedures and outcomes of children who have undergone operations for perforated duodenal ulcers. We report our e...

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Autores principales: Yildiz, Turan, Ilce, Huri Tilla, Ceran, Canan, Ilce, Zekeriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publicaitons 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048492/
https://www.ncbi.nlm.nih.gov/pubmed/24948965
http://dx.doi.org/10.12669/pjms.303.4705
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author Yildiz, Turan
Ilce, Huri Tilla
Ceran, Canan
Ilce, Zekeriya
author_facet Yildiz, Turan
Ilce, Huri Tilla
Ceran, Canan
Ilce, Zekeriya
author_sort Yildiz, Turan
collection PubMed
description Objective: Peptic ulcer disease in children is rare. Therefore, the diagnosis can be missed until complications such as perforation or hemorrhage occur. Few reports have investigated the procedures and outcomes of children who have undergone operations for perforated duodenal ulcers. We report our experience with the modified Graham technique for perforated duodenal ulcers in nine children and review the literature. Methods : The records of patients operated on for a perforated duodenal ulcer in the last 8 years in two pediatric surgery centers were evaluated retrospectively. Patient demographics, symptoms, time to admission to hospital, operative findings, and postoperative clinical course were evaluated. Results : Nine children (mean age 13.2 years, range 6–170 years) were included. All patients were admitted in the first six hours after their abdominal pain started. In three patients, there was free air on plain x-rays, while the x-rays were normal in six. All perforations were located on the anterior surface of the first part of the duodenum and repaired with primary suturing and Graham patch omentoplasty. The recovery was uneventful in all patients. In five patients, urea breath tests were performed postoperatively for Helicobacter Pylori, and the results were positive. All patients underwent triple therapy with lansoprazole, amoxicillin, and clarithromycin. The mean follow-up time was 58 (range 3–94) months. Conclusions : Peptic ulcer perforation should be suspected in children who have acute abdominal pain and peritoneal signs, especially when their suffering is intense. The simple patch repair and postoperative triple therapy for Helicobacter Pylori are safe and satisfactory for treating peptic ulcer perforation in children.
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spelling pubmed-40484922014-06-19 Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication Yildiz, Turan Ilce, Huri Tilla Ceran, Canan Ilce, Zekeriya Pak J Med Sci Original Article Objective: Peptic ulcer disease in children is rare. Therefore, the diagnosis can be missed until complications such as perforation or hemorrhage occur. Few reports have investigated the procedures and outcomes of children who have undergone operations for perforated duodenal ulcers. We report our experience with the modified Graham technique for perforated duodenal ulcers in nine children and review the literature. Methods : The records of patients operated on for a perforated duodenal ulcer in the last 8 years in two pediatric surgery centers were evaluated retrospectively. Patient demographics, symptoms, time to admission to hospital, operative findings, and postoperative clinical course were evaluated. Results : Nine children (mean age 13.2 years, range 6–170 years) were included. All patients were admitted in the first six hours after their abdominal pain started. In three patients, there was free air on plain x-rays, while the x-rays were normal in six. All perforations were located on the anterior surface of the first part of the duodenum and repaired with primary suturing and Graham patch omentoplasty. The recovery was uneventful in all patients. In five patients, urea breath tests were performed postoperatively for Helicobacter Pylori, and the results were positive. All patients underwent triple therapy with lansoprazole, amoxicillin, and clarithromycin. The mean follow-up time was 58 (range 3–94) months. Conclusions : Peptic ulcer perforation should be suspected in children who have acute abdominal pain and peritoneal signs, especially when their suffering is intense. The simple patch repair and postoperative triple therapy for Helicobacter Pylori are safe and satisfactory for treating peptic ulcer perforation in children. Professional Medical Publicaitons 2014 /pmc/articles/PMC4048492/ /pubmed/24948965 http://dx.doi.org/10.12669/pjms.303.4705 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yildiz, Turan
Ilce, Huri Tilla
Ceran, Canan
Ilce, Zekeriya
Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title_full Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title_fullStr Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title_full_unstemmed Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title_short Simple Patch Closure for Perforated Peptic Ulcer in Children Followed by Helicobacter Pylori Eradication
title_sort simple patch closure for perforated peptic ulcer in children followed by helicobacter pylori eradication
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048492/
https://www.ncbi.nlm.nih.gov/pubmed/24948965
http://dx.doi.org/10.12669/pjms.303.4705
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