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Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?

Objective: To evaluate the clinical outcome of emergency and elective operation of splenectomy with periesophagogastric devascularization in treating upper gastrointestinal hemorrhage resulted from portal hypertension. Methods: We retrospectively reviewed 219 patients of upper gastrointestinal hemor...

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Autor principal: Liu, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publicaitons 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048509/
https://www.ncbi.nlm.nih.gov/pubmed/24948982
http://dx.doi.org/10.12669/pjms.303.4520
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author Liu, Sen
author_facet Liu, Sen
author_sort Liu, Sen
collection PubMed
description Objective: To evaluate the clinical outcome of emergency and elective operation of splenectomy with periesophagogastric devascularization in treating upper gastrointestinal hemorrhage resulted from portal hypertension. Methods: We retrospectively reviewed 219 patients of upper gastrointestinal hemorrhage resulted from portal hypertension treated using emergency or elective operation between Jul 2002 and Aug 2010. The clinical data were collected and analyzed. Results: In the group of elective operation, four patients with grade B and three with grade C died, and in the group of emergency operation, two patients with Grade B and four with Grade C died. The Grade C patients treated using emergency operation presented with a higher mortality than those treated using elective operation, but no significant difference was found (p>0.05). In the two groups, no patients with Grade A died. 17 cases (11.1%) suffered from complications in the group of elective operation and 11 cases (16.7 %) in emergency operation (p>0.05). The complication rate in patients with Grade C is significantly higher than that in patients with Grade A or B in each group (p<0.05). The hospital stay and cost in group of elective operation are significantly higher than those in group of emergency operation (p<0.05). Conclusion: The patients with Grade A or B treated using emergency operation have similar clinical outcomes as those treated using elective operation, but emergency operation may result in higher rate of death and complication in patients with Grade C.
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spelling pubmed-40485092014-06-19 Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation? Liu, Sen Pak J Med Sci Original Article Objective: To evaluate the clinical outcome of emergency and elective operation of splenectomy with periesophagogastric devascularization in treating upper gastrointestinal hemorrhage resulted from portal hypertension. Methods: We retrospectively reviewed 219 patients of upper gastrointestinal hemorrhage resulted from portal hypertension treated using emergency or elective operation between Jul 2002 and Aug 2010. The clinical data were collected and analyzed. Results: In the group of elective operation, four patients with grade B and three with grade C died, and in the group of emergency operation, two patients with Grade B and four with Grade C died. The Grade C patients treated using emergency operation presented with a higher mortality than those treated using elective operation, but no significant difference was found (p>0.05). In the two groups, no patients with Grade A died. 17 cases (11.1%) suffered from complications in the group of elective operation and 11 cases (16.7 %) in emergency operation (p>0.05). The complication rate in patients with Grade C is significantly higher than that in patients with Grade A or B in each group (p<0.05). The hospital stay and cost in group of elective operation are significantly higher than those in group of emergency operation (p<0.05). Conclusion: The patients with Grade A or B treated using emergency operation have similar clinical outcomes as those treated using elective operation, but emergency operation may result in higher rate of death and complication in patients with Grade C. Professional Medical Publicaitons 2014 /pmc/articles/PMC4048509/ /pubmed/24948982 http://dx.doi.org/10.12669/pjms.303.4520 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Liu, Sen
Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title_full Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title_fullStr Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title_full_unstemmed Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title_short Management of upper gastrointestinal bleeding from portal hypertension: Elective or emergency operation?
title_sort management of upper gastrointestinal bleeding from portal hypertension: elective or emergency operation?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048509/
https://www.ncbi.nlm.nih.gov/pubmed/24948982
http://dx.doi.org/10.12669/pjms.303.4520
work_keys_str_mv AT liusen managementofuppergastrointestinalbleedingfromportalhypertensionelectiveoremergencyoperation