Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1

The megakaryoblastic leukemia 1 (MKL1) protein functions as a transcriptional coactivator of the serum response factor. MKL1 has three RPEL motifs (RPEL1, RPEL2, and RPEL3) in its N-terminal region. MKL1 binds to monomeric G-actin through RPEL motifs, and the dissociation of MKL1 from G-actin promot...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizuguchi, Mineyuki, Fuju, Takahiro, Obita, Takayuki, Ishikawa, Mitsuru, Tsuda, Masaaki, Tabuchi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048911/
https://www.ncbi.nlm.nih.gov/pubmed/24909411
http://dx.doi.org/10.1038/srep05224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048911/
https://www.ncbi.nlm.nih.gov/pubmed/24909411
http://dx.doi.org/10.1038/srep05224

Ejemplares similares