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Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1

The megakaryoblastic leukemia 1 (MKL1) protein functions as a transcriptional coactivator of the serum response factor. MKL1 has three RPEL motifs (RPEL1, RPEL2, and RPEL3) in its N-terminal region. MKL1 binds to monomeric G-actin through RPEL motifs, and the dissociation of MKL1 from G-actin promot...

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Detalles Bibliográficos
Autores principales:	Mizuguchi, Mineyuki, Fuju, Takahiro, Obita, Takayuki, Ishikawa, Mitsuru, Tsuda, Masaaki, Tabuchi, Akiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048911/ https://www.ncbi.nlm.nih.gov/pubmed/24909411 http://dx.doi.org/10.1038/srep05224

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