Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers

[Image: see text] Monoselective γ-C–H olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quatern...

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Autores principales: Li, Suhua, Chen, Gang, Feng, Chen-Guo, Gong, Wei, Yu, Jin-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049142/
https://www.ncbi.nlm.nih.gov/pubmed/24666182
http://dx.doi.org/10.1021/ja501689j
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author Li, Suhua
Chen, Gang
Feng, Chen-Guo
Gong, Wei
Yu, Jin-Quan
author_facet Li, Suhua
Chen, Gang
Feng, Chen-Guo
Gong, Wei
Yu, Jin-Quan
author_sort Li, Suhua
collection PubMed
description [Image: see text] Monoselective γ-C–H olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quaternary carbon centers at the β-position of aliphatic acids.
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spelling pubmed-40491422015-03-26 Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers Li, Suhua Chen, Gang Feng, Chen-Guo Gong, Wei Yu, Jin-Quan J Am Chem Soc [Image: see text] Monoselective γ-C–H olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quaternary carbon centers at the β-position of aliphatic acids. American Chemical Society 2014-03-26 2014-04-09 /pmc/articles/PMC4049142/ /pubmed/24666182 http://dx.doi.org/10.1021/ja501689j Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Li, Suhua
Chen, Gang
Feng, Chen-Guo
Gong, Wei
Yu, Jin-Quan
Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title_full Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title_fullStr Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title_full_unstemmed Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title_short Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
title_sort ligand-enabled γ-c–h olefination and carbonylation: construction of β-quaternary carbon centers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049142/
https://www.ncbi.nlm.nih.gov/pubmed/24666182
http://dx.doi.org/10.1021/ja501689j
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AT gongwei ligandenabledgcholefinationandcarbonylationconstructionofbquaternarycarboncenters
AT yujinquan ligandenabledgcholefinationandcarbonylationconstructionofbquaternarycarboncenters

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