Emission Tuning of Fluorescent Kinase Inhibitors: Conjugation Length and Substituent Effects

[Image: see text] Fluorescent N-phenyl-4-aminoquinazoline probes targeting the ATP-binding pocket of the ERBB family of receptor tyrosine kinases are reported. Extension of the aromatic quinazoline core with fluorophore “arms” through substitution at the 6- position of the quinazoline core with phen...

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Detalles Bibliográficos
Autores principales: Dhuguru, Jyothi, Liu, Wenjun, Gonzalez, Walter G., Babinchak, W. Michael, Miksovska, Jaroslava, Landgraf, Ralf, Wilson, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049246/
https://www.ncbi.nlm.nih.gov/pubmed/24784897
http://dx.doi.org/10.1021/jo500520x

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