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C5-Alkynyl-Functionalized α-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability

[Image: see text] Major efforts are currently being devoted to improving the binding affinity, target specificity, and enzymatic stability of oligonucleotides used for nucleic acid targeting applications in molecular biology, biotechnology, and medicinal chemistry. One of the most popular strategies...

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Detalles Bibliográficos
Autores principales:	Kumar, Pawan, Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Østergaard, Michael E., Sharma, Pawan K., Hrdlicka, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049248/ https://www.ncbi.nlm.nih.gov/pubmed/24797769 http://dx.doi.org/10.1021/jo5006153

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