Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology

Spinal muscular atrophy (SMA) is characterized by motor neuron loss, caused by mutations or deletions in the ubiquitously expressed survival motor neuron 1 (SMN1) gene. We recently identified a novel role for Smn protein in glucose metabolism and pancreatic development in both an intermediate SMA mo...

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Detalles Bibliográficos
Autores principales: Bowerman, Melissa, Michalski, John-Paul, Beauvais, Ariane, Murray, Lyndsay M., DeRepentigny, Yves, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049303/
https://www.ncbi.nlm.nih.gov/pubmed/24497575
http://dx.doi.org/10.1093/hmg/ddu052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049303/
https://www.ncbi.nlm.nih.gov/pubmed/24497575
http://dx.doi.org/10.1093/hmg/ddu052

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