Cargando…
C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
Intronic expansion of a hexanucleotide GGGGCC repeat in the chromosome 9 open reading frame 72 (C9ORF72) gene is the major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. However, the cellular function of the C9ORF72 protein remains unknown. Here, we demonstrate th...
Autores principales: | Farg, Manal A., Sundaramoorthy, Vinod, Sultana, Jessica M., Yang, Shu, Atkinson, Rachel A.K., Levina, Vita, Halloran, Mark A., Gleeson, Paul A., Blair, Ian P., Soo, Kai Y., King, Anna E., Atkin, Julie D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049310/ https://www.ncbi.nlm.nih.gov/pubmed/24549040 http://dx.doi.org/10.1093/hmg/ddu068 |
Ejemplares similares
-
C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
por: Farg, Manal A, et al.
Publicado: (2017) -
Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
por: Mizielinska, Sarah, et al.
Publicado: (2017) -
Assessment of psychiatric changes in C9ORF72 frontotemporal dementia
por: Hornberger, Michael
Publicado: (2012) -
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit
por: Sattler, Rita, et al.
Publicado: (2023) -
Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia
por: Fratta, Pietro, et al.
Publicado: (2013)