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Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process

Nonepileptic seizures (NES) apparently look like epileptic seizures, but are not associated with ictal electrical discharges in the brain. NES constitute one of the most important differential diagnoses of epilepsy. They have been recognized as a distinctive clinical phenomenon for centuries, and vi...

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Autores principales: Anzellotti, Francesca, Franciotti, Raffaella, Zhuzhuni, Holta, D’Amico, Aurelio, Thomas, Astrid, Onofrj, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049430/
https://www.ncbi.nlm.nih.gov/pubmed/24926197
http://dx.doi.org/10.2147/NDT.S60089
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author Anzellotti, Francesca
Franciotti, Raffaella
Zhuzhuni, Holta
D’Amico, Aurelio
Thomas, Astrid
Onofrj, Marco
author_facet Anzellotti, Francesca
Franciotti, Raffaella
Zhuzhuni, Holta
D’Amico, Aurelio
Thomas, Astrid
Onofrj, Marco
author_sort Anzellotti, Francesca
collection PubMed
description Nonepileptic seizures (NES) apparently look like epileptic seizures, but are not associated with ictal electrical discharges in the brain. NES constitute one of the most important differential diagnoses of epilepsy. They have been recognized as a distinctive clinical phenomenon for centuries, and video/electroencephalogram monitoring has allowed clinicians to make near-certain diagnoses. NES are supposedly unrelated to organic brain lesions, and despite the preponderance of a psychiatric/psychological context, they may have an iatrogenic origin. We report a patient with NES precipitated by levetiracetam therapy; in this case, NES was observed during the disappearance of epileptiform discharges from the routine video/electroencephalogram. We discuss the possible mechanisms underlying NES with regard to alternative psychoses associated with the phenomenon of the forced normalization process.
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spelling pubmed-40494302014-06-12 Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process Anzellotti, Francesca Franciotti, Raffaella Zhuzhuni, Holta D’Amico, Aurelio Thomas, Astrid Onofrj, Marco Neuropsychiatr Dis Treat Case Report Nonepileptic seizures (NES) apparently look like epileptic seizures, but are not associated with ictal electrical discharges in the brain. NES constitute one of the most important differential diagnoses of epilepsy. They have been recognized as a distinctive clinical phenomenon for centuries, and video/electroencephalogram monitoring has allowed clinicians to make near-certain diagnoses. NES are supposedly unrelated to organic brain lesions, and despite the preponderance of a psychiatric/psychological context, they may have an iatrogenic origin. We report a patient with NES precipitated by levetiracetam therapy; in this case, NES was observed during the disappearance of epileptiform discharges from the routine video/electroencephalogram. We discuss the possible mechanisms underlying NES with regard to alternative psychoses associated with the phenomenon of the forced normalization process. Dove Medical Press 2014-05-23 /pmc/articles/PMC4049430/ /pubmed/24926197 http://dx.doi.org/10.2147/NDT.S60089 Text en © 2014 Anzellotti et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Anzellotti, Francesca
Franciotti, Raffaella
Zhuzhuni, Holta
D’Amico, Aurelio
Thomas, Astrid
Onofrj, Marco
Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title_full Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title_fullStr Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title_full_unstemmed Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title_short Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
title_sort nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049430/
https://www.ncbi.nlm.nih.gov/pubmed/24926197
http://dx.doi.org/10.2147/NDT.S60089
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