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Social phobia in Parkinson’s disease: Prevalence and risk factors

OBJECTIVE: We aimed to investigate the frequency of social phobia in patients with Parkinson’s disease (PD). In addition, we explored the relationship between social phobia and the clinical characteristics of PD, and the frequency of comorbid psychiatric disorders in PD patients. METHODS: This study...

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Autores principales: Gultekin, Bulent Kadri, Ozdilek, Betul, Bestepe, Engin Emrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049431/
https://www.ncbi.nlm.nih.gov/pubmed/24926195
http://dx.doi.org/10.2147/NDT.S62942
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author Gultekin, Bulent Kadri
Ozdilek, Betul
Bestepe, Engin Emrem
author_facet Gultekin, Bulent Kadri
Ozdilek, Betul
Bestepe, Engin Emrem
author_sort Gultekin, Bulent Kadri
collection PubMed
description OBJECTIVE: We aimed to investigate the frequency of social phobia in patients with Parkinson’s disease (PD). In addition, we explored the relationship between social phobia and the clinical characteristics of PD, and the frequency of comorbid psychiatric disorders in PD patients. METHODS: This study included 80 consecutive patients with PD admitted to the Parkinson’s disease and Movement Disorders Clinic at the Erenkoy Research and Training Hospital for Neurologic and Psychiatric Disorders, Istanbul, Turkey and used demographic and clinical data. The PD patients were evaluated during the “on state”, using the Hoehn and Yahr scale, the Unified Parkinson’s Disease Rating Scale, and the Schwab England Activities of Daily Living Scale. Psychiatric evaluations were conducted using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition structured clinical interview, the Liebowitz Social Anxiety Scale (LSAS), and the Hamilton Depression Rating Scale. RESULTS: Social phobia was diagnosed in 42.5% of PD patients. Social phobia was comorbid with depression in 20 patients (58.8%), generalized anxiety disorder in 18 patients (52.9%), and panic disorder in six patients (17.6%). Social phobia was more frequent in males, early-onset PD, patients with a long duration of disease, the presence of postural instability, and with the use of a high Levodopa equivalent daily dose. A logistic regression analysis revealed the predictive factors of social phobia to be the sex of the patient (more frequent in males) and the presence of postural instability. There was a statistically significantly negative correlation between the LSAS score and the age of disease onset (r=−0.503; P=0.002) and a positive correlation between LSAS score and the duration of disease (r=0.374; P=0.023). CONCLUSION: Social phobia is frequently observed in PD patients. Therefore, the assessment of PD patients should always include psychiatric evaluations, particularly for social phobia. The early detection and treatment of social phobia in PD patients is very important for the quality of life of patients as well as caregivers.
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spelling pubmed-40494312014-06-12 Social phobia in Parkinson’s disease: Prevalence and risk factors Gultekin, Bulent Kadri Ozdilek, Betul Bestepe, Engin Emrem Neuropsychiatr Dis Treat Original Research OBJECTIVE: We aimed to investigate the frequency of social phobia in patients with Parkinson’s disease (PD). In addition, we explored the relationship between social phobia and the clinical characteristics of PD, and the frequency of comorbid psychiatric disorders in PD patients. METHODS: This study included 80 consecutive patients with PD admitted to the Parkinson’s disease and Movement Disorders Clinic at the Erenkoy Research and Training Hospital for Neurologic and Psychiatric Disorders, Istanbul, Turkey and used demographic and clinical data. The PD patients were evaluated during the “on state”, using the Hoehn and Yahr scale, the Unified Parkinson’s Disease Rating Scale, and the Schwab England Activities of Daily Living Scale. Psychiatric evaluations were conducted using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition structured clinical interview, the Liebowitz Social Anxiety Scale (LSAS), and the Hamilton Depression Rating Scale. RESULTS: Social phobia was diagnosed in 42.5% of PD patients. Social phobia was comorbid with depression in 20 patients (58.8%), generalized anxiety disorder in 18 patients (52.9%), and panic disorder in six patients (17.6%). Social phobia was more frequent in males, early-onset PD, patients with a long duration of disease, the presence of postural instability, and with the use of a high Levodopa equivalent daily dose. A logistic regression analysis revealed the predictive factors of social phobia to be the sex of the patient (more frequent in males) and the presence of postural instability. There was a statistically significantly negative correlation between the LSAS score and the age of disease onset (r=−0.503; P=0.002) and a positive correlation between LSAS score and the duration of disease (r=0.374; P=0.023). CONCLUSION: Social phobia is frequently observed in PD patients. Therefore, the assessment of PD patients should always include psychiatric evaluations, particularly for social phobia. The early detection and treatment of social phobia in PD patients is very important for the quality of life of patients as well as caregivers. Dove Medical Press 2014-05-21 /pmc/articles/PMC4049431/ /pubmed/24926195 http://dx.doi.org/10.2147/NDT.S62942 Text en © 2014 Gultekin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Gultekin, Bulent Kadri
Ozdilek, Betul
Bestepe, Engin Emrem
Social phobia in Parkinson’s disease: Prevalence and risk factors
title Social phobia in Parkinson’s disease: Prevalence and risk factors
title_full Social phobia in Parkinson’s disease: Prevalence and risk factors
title_fullStr Social phobia in Parkinson’s disease: Prevalence and risk factors
title_full_unstemmed Social phobia in Parkinson’s disease: Prevalence and risk factors
title_short Social phobia in Parkinson’s disease: Prevalence and risk factors
title_sort social phobia in parkinson’s disease: prevalence and risk factors
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049431/
https://www.ncbi.nlm.nih.gov/pubmed/24926195
http://dx.doi.org/10.2147/NDT.S62942
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