Cargando…
Thermodynamics of the DNA Damage Repair Steps of Human 8-Oxoguanine DNA Glycosylase
Human 8-oxoguanine DNA glycosylase (hOGG1) is a key enzyme responsible for initiating the base excision repair of 7,8-dihydro-8-oxoguanosine (oxoG). In this study a thermodynamic analysis of the interaction of hOGG1 with specific and non-specific DNA-substrates is performed based on stopped-flow kin...
Autores principales: | Kuznetsov, Nikita A., Kuznetsova, Alexandra A., Vorobjev, Yuri N., Krasnoperov, Lev N., Fedorova, Olga S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049573/ https://www.ncbi.nlm.nih.gov/pubmed/24911585 http://dx.doi.org/10.1371/journal.pone.0098495 |
Ejemplares similares
-
Thermodynamics of the multi-stage DNA lesion recognition and repair by formamidopyrimidine-DNA glycosylase using pyrrolocytosine fluorescence—stopped-flow pre-steady-state kinetics
por: Kuznetsov, Nikita A., et al.
Publicado: (2012) -
Kinetics and Thermodynamics of DNA Processing by Wild Type DNA-Glycosylase Endo III and Its Catalytically Inactive Mutant Forms
por: Kladova, Olga A., et al.
Publicado: (2018) -
Thermodynamic and kinetic basis for recognition and repair of 8-oxoguanine in DNA by human 8-oxoguanine-DNA glycosylase
por: Kirpota, Oleg O., et al.
Publicado: (2011) -
Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase
por: Kuznetsov, Nikita A., et al.
Publicado: (2005) -
Lesion Recognition and Cleavage of Damage-Containing Quadruplexes and Bulged Structures by DNA Glycosylases
por: Kuznetsova, Alexandra A., et al.
Publicado: (2020)