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Early detection of thrombin activity in neuroinflammatory disease

Although multiple sclerosis (MS) has been associated with the coagulation system, the temporal and spatial regulation of coagulation activity in neuroinflammatory lesions is unknown. Using a novel molecular probe, we characterized the activity pattern of thrombin, the central protease of the coagula...

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Detalles Bibliográficos
Autores principales: Davalos, Dimitrios, Baeten, Kim M, Whitney, Michael A, Mullins, Eric S, Friedman, Beth, Olson, Emilia S, Ryu, Jae Kyu, Smirnoff, Dimitri S, Petersen, Mark A, Bedard, Catherine, Degen, Jay L, Tsien, Roger Y, Akassoglou, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049631/
https://www.ncbi.nlm.nih.gov/pubmed/24740641
http://dx.doi.org/10.1002/ana.24078