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Early detection of thrombin activity in neuroinflammatory disease
Although multiple sclerosis (MS) has been associated with the coagulation system, the temporal and spatial regulation of coagulation activity in neuroinflammatory lesions is unknown. Using a novel molecular probe, we characterized the activity pattern of thrombin, the central protease of the coagula...
Autores principales: | Davalos, Dimitrios, Baeten, Kim M, Whitney, Michael A, Mullins, Eric S, Friedman, Beth, Olson, Emilia S, Ryu, Jae Kyu, Smirnoff, Dimitri S, Petersen, Mark A, Bedard, Catherine, Degen, Jay L, Tsien, Roger Y, Akassoglou, Katerina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049631/ https://www.ncbi.nlm.nih.gov/pubmed/24740641 http://dx.doi.org/10.1002/ana.24078 |
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