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Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke
Edaravone, a potent antioxidant, may improve thrombolytic therapy because it benefits ischemic stroke patients on its own and mitigates adverse effects of tissue plasminogen activator (tPA) in preclinical models. However, whether the combined tPA-edaravone therapy is more effective in reducing infar...
Autores principales: | Sun, Yu-Yo, Morozov, Yury M., Yang, Dianer, Li, Yikun, Dunn, R. Scott, Rakic, Pasko, Chan, Pak H., Abe, Koji, Lindquist, Diana M., Kuan, Chia-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049665/ https://www.ncbi.nlm.nih.gov/pubmed/24911517 http://dx.doi.org/10.1371/journal.pone.0098807 |
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