Cargando…

Modulation of microRNA expression in human lung cancer cells by the G9a histone methyltransferase inhibitor BIX01294

MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of their target genes at the post-transcriptional level. In cancer cells, miRNAs, depending on the biological functions of their target genes, may have a tumor-promoting or -suppressing effect. Treatment of cancer cells with i...

Descripción completa

Detalles Bibliográficos
Autores principales:	PANG, ALAN LAP-YIN, TITLE, ALEXANDRA C., RENNERT, OWEN M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049738/ https://www.ncbi.nlm.nih.gov/pubmed/24932239 http://dx.doi.org/10.3892/ol.2014.2034

Ejemplares similares

The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis
por: Oh, Su Young, et al.
Publicado: (2015)

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
por: Chang, Yanqi, et al.
Publicado: (2009)

The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission
por: Ngwa, Che Julius, et al.
Publicado: (2019)

BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells
por: Ciechomska, Iwona Anna, et al.
Publicado: (2016)

Pre-treatment or Post-treatment of Human Glioma Cells With BIX01294, the Inhibitor of Histone Methyltransferase G9a, Sensitizes Cells to Temozolomide
por: Ciechomska, Iwona Anna, et al.
Publicado: (2018)

Mechanism of G9a inhibitor BIX-01294 acting on U251 glioma cells
por: Guo, Ai-Shun, et al.
Publicado: (2016)

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity
por: Rotili, Dante, et al.
Publicado: (2014)

Examining the effects of the histone methyltransferase inhibitor BIX-01294 on histone modifications and gene expression in both a clinical population and mouse models
por: Chase, Kayla A., et al.
Publicado: (2019)

Inhibition of Histone H3K9 Methylation by BIX-01294 Promotes Stress-Induced Microspore Totipotency and Enhances Embryogenesis Initiation
por: Berenguer, Eduardo, et al.
Publicado: (2017)

BIX‐01294 enhanced chemotherapy effect in gastric cancer by inducing GSDME‐mediated pyroptosis
por: Deng, Bei‐Bei, et al.
Publicado: (2020)

TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos
por: Cao, Zubing, et al.
Publicado: (2017)

Nicotinamide activates latent HIV-1 ex vivo in ART suppressed individuals, revealing higher potency than the association of two methyltransferase inhibitors, chaetocin and BIX01294
por: Samer, Sadia, et al.
Publicado: (2020)

Effect of BIX-01294 on H3K9me2 levels and the imprinted gene Snrpn in mouse embryonic fibroblast cells
por: Chen, Peng, et al.
Publicado: (2015)

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells
por: Cui, Jing, et al.
Publicado: (2015)

EHMT2 inhibitor BIX-01294 induces endoplasmic reticulum stress mediated apoptosis and autophagy in diffuse large B-cell lymphoma cells
por: Xu, Linyan, et al.
Publicado: (2021)

The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death
por: Fan, Jia-Dong, et al.
Publicado: (2015)

BIX01294 inhibits EGFR signaling in EGFR-mutant lung adenocarcinoma cells through a BCKDHA-mediated reduction in the EGFR level
por: Kim, Ji Hye, et al.
Publicado: (2021)

BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
por: Woo, Seon Min, et al.
Publicado: (2018)

Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain
por: Asadi, Sareh, et al.
Publicado: (2015)

Functional Role of G9a Histone Methyltransferase in Cancer
por: Casciello, Francesco, et al.
Publicado: (2015)

Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma
por: Bellamy, Jacob, et al.
Publicado: (2020)

Uptake and Function Studies of Maternal Milk-derived MicroRNAs
por: Title, Alexandra C., et al.
Publicado: (2015)

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia
por: Pappano, William N., et al.
Publicado: (2015)

Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
por: Lei, Wenjing, et al.
Publicado: (2015)

Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a
por: An, Phan Nguyen Thuy, et al.
Publicado: (2017)

Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Prognostic value of lymphocyte-to-monocyte ratio and histone methyltransferase G9a histone methyltransferase in patients with double expression lymphoma: A retrospective observational study
por: Xu, Pei, et al.
Publicado: (2021)

A case study in cross-talk: the histone lysine methyltransferases G9a and GLP
por: Collins, Robert, et al.
Publicado: (2010)

The histone methyltransferase G9a regulates tolerance to oxidative stress–induced energy consumption
por: Riahi, Human, et al.
Publicado: (2019)

Targets of histone H3 lysine 9 methyltransferases
por: Levinsky, Aidan J., et al.
Publicado: (2022)

Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma
por: Watson, Zachary L., et al.
Publicado: (2019)

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity
por: Sundriyal, Sandeep, et al.
Publicado: (2017)

Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase
por: Estève, Pierre-Olivier, et al.
Publicado: (2005)

Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function
por: Lehnertz, Bernhard, et al.
Publicado: (2010)

Histone methyltransferase G9a is a key regulator of the starvation-induced behaviors in Drosophila melanogaster
por: Shimaji, Kouhei, et al.
Publicado: (2017)

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer
por: Pan, Mei-Ren, et al.
Publicado: (2016)

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma
por: Yokoyama, Masayuki, et al.
Publicado: (2017)

Histone methyltransferase G9a protects against acute liver injury through GSTP1
por: Zhang, Yu, et al.
Publicado: (2019)

Evaluation of performance for IBARAKI biological crystal diffractometer iBIX with new detectors
por: Kusaka, Katsuhiro, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hume75rsdgsid9egae1qjeocf8