Cargando…

Misdiagnosed gastrinoma: A case report

Gastrinoma is most commonly located in the gastrinoma triangle (comprising of the duodenum, pancreas and bile ducts) or in the adjacent lymph nodes. Due to the low mortality rate, it is often misdiagnosed as other diseases with similar clinical characteristics, such as a solid pseudopapillary tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: SUN, QI-KAI, WANG, WEI, ZHOU, HANG-CHENG, LV, YANG, YU, JI-HAI, MA, JIN-LIANG, JIA, WEI-DONG, XU, GE-LIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049751/
https://www.ncbi.nlm.nih.gov/pubmed/24932294
http://dx.doi.org/10.3892/ol.2014.2019
_version_ 1782319864904417280
author SUN, QI-KAI
WANG, WEI
ZHOU, HANG-CHENG
LV, YANG
YU, JI-HAI
MA, JIN-LIANG
JIA, WEI-DONG
XU, GE-LIANG
author_facet SUN, QI-KAI
WANG, WEI
ZHOU, HANG-CHENG
LV, YANG
YU, JI-HAI
MA, JIN-LIANG
JIA, WEI-DONG
XU, GE-LIANG
author_sort SUN, QI-KAI
collection PubMed
description Gastrinoma is most commonly located in the gastrinoma triangle (comprising of the duodenum, pancreas and bile ducts) or in the adjacent lymph nodes. Due to the low mortality rate, it is often misdiagnosed as other diseases with similar clinical characteristics, such as a solid pseudopapillary tumor of the pancreas (SPTP). Therefore, the current study reports a rare case of gastrinoma located in the tail of the pancreas of a female patient under medical examination, who exhibited no clinical symptoms. The tumor, which was located in the body and tail of the pancreas, was successfully resected and the spleen was preserved. The outcome of surgery combined with the postoperative pathological examination resulted in the patient being misdiagnosed with a SPTP. During the consequent six-year follow-up period, low-density liver lesions and an intractable peptic ulcer gradually appeared. Finally, the patient diagnosis was confirmed as a malignant pancreatic neuroendocrine carcinoma with liver metastases. On June 1, 2011, a liver transplant was successfully performed and the patient has maintained a good overall condition. The underlying clinical and pathological factors that may have resulted in misdiagnosis are investigated in the present study. Through providing our preliminary clinical experiences and lessons, the aim of the present study was to focus the attention of clinicians on this type of cancer in order to improve its diagnosis and treatment.
format Online
Article
Text
id pubmed-4049751
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-40497512014-06-13 Misdiagnosed gastrinoma: A case report SUN, QI-KAI WANG, WEI ZHOU, HANG-CHENG LV, YANG YU, JI-HAI MA, JIN-LIANG JIA, WEI-DONG XU, GE-LIANG Oncol Lett Articles Gastrinoma is most commonly located in the gastrinoma triangle (comprising of the duodenum, pancreas and bile ducts) or in the adjacent lymph nodes. Due to the low mortality rate, it is often misdiagnosed as other diseases with similar clinical characteristics, such as a solid pseudopapillary tumor of the pancreas (SPTP). Therefore, the current study reports a rare case of gastrinoma located in the tail of the pancreas of a female patient under medical examination, who exhibited no clinical symptoms. The tumor, which was located in the body and tail of the pancreas, was successfully resected and the spleen was preserved. The outcome of surgery combined with the postoperative pathological examination resulted in the patient being misdiagnosed with a SPTP. During the consequent six-year follow-up period, low-density liver lesions and an intractable peptic ulcer gradually appeared. Finally, the patient diagnosis was confirmed as a malignant pancreatic neuroendocrine carcinoma with liver metastases. On June 1, 2011, a liver transplant was successfully performed and the patient has maintained a good overall condition. The underlying clinical and pathological factors that may have resulted in misdiagnosis are investigated in the present study. Through providing our preliminary clinical experiences and lessons, the aim of the present study was to focus the attention of clinicians on this type of cancer in order to improve its diagnosis and treatment. D.A. Spandidos 2014-06 2014-04-01 /pmc/articles/PMC4049751/ /pubmed/24932294 http://dx.doi.org/10.3892/ol.2014.2019 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
SUN, QI-KAI
WANG, WEI
ZHOU, HANG-CHENG
LV, YANG
YU, JI-HAI
MA, JIN-LIANG
JIA, WEI-DONG
XU, GE-LIANG
Misdiagnosed gastrinoma: A case report
title Misdiagnosed gastrinoma: A case report
title_full Misdiagnosed gastrinoma: A case report
title_fullStr Misdiagnosed gastrinoma: A case report
title_full_unstemmed Misdiagnosed gastrinoma: A case report
title_short Misdiagnosed gastrinoma: A case report
title_sort misdiagnosed gastrinoma: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049751/
https://www.ncbi.nlm.nih.gov/pubmed/24932294
http://dx.doi.org/10.3892/ol.2014.2019
work_keys_str_mv AT sunqikai misdiagnosedgastrinomaacasereport
AT wangwei misdiagnosedgastrinomaacasereport
AT zhouhangcheng misdiagnosedgastrinomaacasereport
AT lvyang misdiagnosedgastrinomaacasereport
AT yujihai misdiagnosedgastrinomaacasereport
AT majinliang misdiagnosedgastrinomaacasereport
AT jiaweidong misdiagnosedgastrinomaacasereport
AT xugeliang misdiagnosedgastrinomaacasereport