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Characterization of rare transforming KRAS mutations in sporadic colorectal cancer

KRAS mutational status has been shown to be a predictive biomarker of resistance to anti-EGFR monoclonal antibody (mAb) therapy in patients with metastatic colorectal cancer. We report the spectrum of KRAS mutation in 1506 patients with colorectal cancer and the identification and characterization o...

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Detalles Bibliográficos
Autores principales:	Tong, Joanna HM, Lung, Raymond WM, Sin, Frankie MC, Law, Peggy PY, Kang, Wei, Chan, Anthony WH, Ma, Brigette BY, Mak, Tony WC, Ng, Simon SM, To, Ka Fai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049792/ https://www.ncbi.nlm.nih.gov/pubmed/24642870 http://dx.doi.org/10.4161/cbt.28550

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