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Delayed Fracture Healing and Increased Callus Adiposity in a C57BL/6J Murine Model of Obesity-Associated Type 2 Diabetes Mellitus
INTRODUCTION: Impaired healing and non-union of skeletal fractures is a major public health problem, with morbidity exacerbated in patients with diabetes mellitus (DM). DM is prevalent worldwide and affects approximately 25.8 million US adults, with >90% having obesity-related type 2 DM (T2DM). W...
Autores principales: | Brown, Matthew L., Yukata, Kiminori, Farnsworth, Christopher W., Chen, Ding-Geng, Awad, Hani, Hilton, Matthew J., O'Keefe, Regis J., Xing, Lianping, Mooney, Robert A., Zuscik, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049817/ https://www.ncbi.nlm.nih.gov/pubmed/24911161 http://dx.doi.org/10.1371/journal.pone.0099656 |
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