Cargando…

The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation

The nuclear receptor, REV-ERBα, has a key role in circadian rhythms and requires heme as its ligand. The present study determined whether the heme precursor, 5-aminolevulinic acid (ALA), affects REV-ERBα and its target genes. When exposed to ALA, the human lung diploid cell line, WI-38, exhibited ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamashita, Kohei, Hagiya, Yuichiro, Nakajima, Motowo, Ishizuka, Masahiro, Tanaka, Tohru, Ogura, Shun-ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050196/ https://www.ncbi.nlm.nih.gov/pubmed/24918048 http://dx.doi.org/10.1016/j.fob.2014.03.010

Ejemplares similares

5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages
por: Sugiyama, Yuta, et al.
Publicado: (2018)

The Effect of Iron Ion on the Specificity of Photodynamic Therapy with 5-Aminolevulinic Acid
por: Hayashi, Maiko, et al.
Publicado: (2015)

The effect of 5-aminolevulinic acid on cytochrome c oxidase activity in mouse liver
por: Ogura, Shun-ichiro, et al.
Publicado: (2011)

Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy
por: Nakayama, Taku, et al.
Publicado: (2016)

The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation
por: Miura, Mai, et al.
Publicado: (2015)

Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)
por: Rehani, Peter R., et al.
Publicado: (2019)

Suppression of angiotensin converting enzyme 2, a host receptor for SARS-CoV-2 infection, using 5-aminolevulinic acid in vitro
por: Nara, Eriko, et al.
Publicado: (2023)

Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors
por: Ishikawa, Toshihisa, et al.
Publicado: (2011)

5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice
por: Saitoh, Shinichi, et al.
Publicado: (2018)

Photodynamic Detection of Peritoneal Metastases Using 5-Aminolevulinic Acid (ALA)
por: Yonemura, Yutaka, et al.
Publicado: (2017)

Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
por: Cho, Han, et al.
Publicado: (2012)

5-Aminolevulinic Acid Attenuates Atherosclerotic Plaque Progression in Low-Density Lipoprotein Receptor-Deficient Mice by Heme Oxygenase-1 Induction
por: Hagisawa, Kohsuke, et al.
Publicado: (2019)

Nuclear receptor Rev-erbα: a heme receptor that coordinates circadian rhythm and metabolism
por: Yin, Lei, et al.
Publicado: (2010)

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ
por: Mosure, Sarah A., et al.
Publicado: (2021)

5-Aminolevulinic acid with ferrous iron improves early renal damage and hepatic steatosis in high fat diet-induced obese mice
por: Kamiya, Atsuko, et al.
Publicado: (2019)

Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation
por: Wang, Wenqian, et al.
Publicado: (2017)

Oxygen Availability for Porphyrin Biosynthesis Enzymes Determines the Production of Protoporphyrin IX (PpIX) during Hypoxia
por: Otsuka, Shimpei, et al.
Publicado: (2015)

REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output
por: Ikeda, Ryosuke, et al.
Publicado: (2019)

Polymeric iron chelators for enhancing 5‐aminolevulinic acid‐induced photodynamic therapy
por: Nomoto, Takahiro, et al.
Publicado: (2022)

Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
por: Amador, Ariadna, et al.
Publicado: (2018)

Impact of 5-aminolevulinic acid with iron supplementation on exercise efficiency and home-based walking training achievement in older women
por: Masuki, Shizue, et al.
Publicado: (2015)

5-aminolevulinic acid combined with ferrous ion reduces adiposity and improves glucose tolerance in diet-induced obese mice via enhancing mitochondrial function
por: Ota, Urara, et al.
Publicado: (2017)

Direct Regulation of CLOCK Expression by REV-ERB
por: Crumbley, Christine, et al.
Publicado: (2011)

Rev-erbs and Glia—Implications for Neurodegenerative Diseases
por: Griffin, Percy, et al.
Publicado: (2019)

REV-ERB is essential in cardiac fibroblasts homeostasis
por: Luo, Xiaokang, et al.
Publicado: (2022)

The Role of REV-ERB Receptors in Cancer Pathogenesis
por: Gomatou, Georgia, et al.
Publicado: (2023)

Efficacy and Safety of 5-Aminolevulinic Acid for Patients with Symptoms of Late-Onset Hypogonadism: A Preliminary Study
por: Koyasu, Hiroki, et al.
Publicado: (2022)

5‐Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death‐ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma model
por: Hu, Xin, et al.
Publicado: (2021)

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
por: Wachowska, Małgorzata, et al.
Publicado: (2011)

Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
por: Amador, Ariadna, et al.
Publicado: (2016)

Expression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regeneration
por: Meier, Volker, et al.
Publicado: (2006)

In Vivo Curative and Protective Potential of Orally Administered 5-Aminolevulinic Acid plus Ferrous Ion against Malaria
por: Suzuki, Shigeo, et al.
Publicado: (2015)

Five-Aminolevulinic Acid (5-ALA) Induces Heme Oxygenase-1 and Ameliorates Palmitic Acid-Induced Endoplasmic Reticulum Stress in Renal Tubules
por: Hamada, Shintaro, et al.
Publicado: (2023)

Antimalarial Drugs Enhance the Cytotoxicity of 5-Aminolevulinic Acid-Based Photodynamic Therapy against the Mammary Tumor Cells of Mice In Vitro
por: Osaki, Tomohiro, et al.
Publicado: (2019)

In vitro evaluation of 5-aminolevulinic acid (ALA) loaded PLGA nanoparticles
por: Shi, Lei, et al.
Publicado: (2013)

Alleviation of Lead Stress on Sage Plant by 5-Aminolevulinic Acid (ALA)
por: El-Shora, Hamed M., et al.
Publicado: (2021)

Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists
por: Solt, Laura A., et al.
Publicado: (2012)

Novel Function of Rev-erbα in Promoting Brown Adipogenesis
por: Nam, Deokhwa, et al.
Publicado: (2015)

Rev-erbα in the brain is essential for circadian food entrainment
por: Delezie, Julien, et al.
Publicado: (2016)

Targeting REV-ERBα for therapeutic purposes: promises and challenges
por: Wang, Shuai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4on8da3djrfnnirbd2fdciaofr