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The Carpathian range represents a weak genetic barrier in South-East Europe

BACKGROUND: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the North of Romania, and 66 from South Romania. RESULTS: We have analyzed their...

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Autores principales: Hervella, Montserrat, Izagirre, Neskuts, Alonso, Santos, Ioana, Mihai, Netea, Mihai G, de-la-Rua, Concepción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050216/
https://www.ncbi.nlm.nih.gov/pubmed/24885208
http://dx.doi.org/10.1186/1471-2156-15-56
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author Hervella, Montserrat
Izagirre, Neskuts
Alonso, Santos
Ioana, Mihai
Netea, Mihai G
de-la-Rua, Concepción
author_facet Hervella, Montserrat
Izagirre, Neskuts
Alonso, Santos
Ioana, Mihai
Netea, Mihai G
de-la-Rua, Concepción
author_sort Hervella, Montserrat
collection PubMed
description BACKGROUND: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the North of Romania, and 66 from South Romania. RESULTS: We have analyzed their mtDNA variability in the context of other European and Near Eastern populations through multivariate analyses. The results show that regarding the mtDNA haplogroup and haplotype distributions the Romanian groups living outside the Carpathian range (South Romania) displayed some degree of genetic differentiation compared to those living within the Carpahian range (North Romania). CONCLUSION: The main differentiation between the mtDNA variability of the groups from North and South Romania can be attributed to the demographic movements from East to West (prehistoric or historic) that differently affected in these regions, suggesting that the Carpathian mountain range represents a weak genetic barrier in South-East Europe.
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spelling pubmed-40502162014-06-11 The Carpathian range represents a weak genetic barrier in South-East Europe Hervella, Montserrat Izagirre, Neskuts Alonso, Santos Ioana, Mihai Netea, Mihai G de-la-Rua, Concepción BMC Genet Research Article BACKGROUND: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the North of Romania, and 66 from South Romania. RESULTS: We have analyzed their mtDNA variability in the context of other European and Near Eastern populations through multivariate analyses. The results show that regarding the mtDNA haplogroup and haplotype distributions the Romanian groups living outside the Carpathian range (South Romania) displayed some degree of genetic differentiation compared to those living within the Carpahian range (North Romania). CONCLUSION: The main differentiation between the mtDNA variability of the groups from North and South Romania can be attributed to the demographic movements from East to West (prehistoric or historic) that differently affected in these regions, suggesting that the Carpathian mountain range represents a weak genetic barrier in South-East Europe. BioMed Central 2014-05-15 /pmc/articles/PMC4050216/ /pubmed/24885208 http://dx.doi.org/10.1186/1471-2156-15-56 Text en Copyright © 2014 Hervella et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hervella, Montserrat
Izagirre, Neskuts
Alonso, Santos
Ioana, Mihai
Netea, Mihai G
de-la-Rua, Concepción
The Carpathian range represents a weak genetic barrier in South-East Europe
title The Carpathian range represents a weak genetic barrier in South-East Europe
title_full The Carpathian range represents a weak genetic barrier in South-East Europe
title_fullStr The Carpathian range represents a weak genetic barrier in South-East Europe
title_full_unstemmed The Carpathian range represents a weak genetic barrier in South-East Europe
title_short The Carpathian range represents a weak genetic barrier in South-East Europe
title_sort carpathian range represents a weak genetic barrier in south-east europe
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050216/
https://www.ncbi.nlm.nih.gov/pubmed/24885208
http://dx.doi.org/10.1186/1471-2156-15-56
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