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Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb
Although the role of noxious α-synuclein (α-SYN) in the degeneration of midbrain dopaminergic neurons and associated motor deficits of Parkinson’s disease is recognized, its impact on non-motor brain circuits and related symptoms remains elusive. Through combining in vivo two-photon imaging with tim...
Autores principales: | Neuner, Johanna, Ovsepian, Saak V., Dorostkar, Mario, Filser, Severin, Gupta, Aayush, Michalakis, Stylianos, Biel, Martin, Herms, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050256/ https://www.ncbi.nlm.nih.gov/pubmed/24867427 http://dx.doi.org/10.1038/ncomms4915 |
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