PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

The transcription factor Tal1 is a critical activator or repressor of gene expression in hematopoiesis and leukaemia. The mechanism by which Tal1 differentially influences transcription of distinct genes is not fully understood. Here we show that Tal1 interacts with the peptidylarginine deiminase IV...

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Detalles Bibliográficos
Autores principales: Kolodziej, Stephan, Kuvardina, Olga N., Oellerich, Thomas, Herglotz, Julia, Backert, Ingo, Kohrs, Nicole, Buscató, Estel.la, Wittmann, Sandra K., Salinas-Riester, Gabriela, Bonig, Halvard, Karas, Michael, Serve, Hubert, Proschak, Ewgenij, Lausen, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050257/
https://www.ncbi.nlm.nih.gov/pubmed/24874575
http://dx.doi.org/10.1038/ncomms4995

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