The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits Porphyromonas gingivalis-induced expression of interleukin-8 by oral keratinocytes

OBJECTIVE: The alpha 7 nicotinic receptor (α7nAChR) is expressed by oral keratinocytes. α7nAChR activation mediates anti-inflammatory responses. The objective of this study was to determine if α7nAChR activation inhibited pathogen-induced interleukin-8 (IL-8) expression by oral keratinocytes. MATERI...

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Detalles Bibliográficos
Autores principales: Macpherson, Alexandrea, Zoheir, Noha, Awang, Raja Azman, Culshaw, Shauna, Ramage, Gordon, Lappin, David F., Nile, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050294/
https://www.ncbi.nlm.nih.gov/pubmed/24609617
http://dx.doi.org/10.1007/s00011-014-0725-5

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