Synthesis of l-Ascorbic Acid Lactone Derivatives

A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were synthesized. Among these lactones, lactones 8–12 were new compounds. The cytotoxicity of...

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Detalles Bibliográficos
Autores principales: Shao, Li-Dong, Wu, Ya-Nan, Xu, Jun, He, Juan, Zhao, Yu, Peng, Li-Yan, Li, Yan, Yang, Yu-Rong, Xia, Cheng-Feng, Zhao, Qin-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050306/
https://www.ncbi.nlm.nih.gov/pubmed/24955300
http://dx.doi.org/10.1007/s13659-014-0022-6
Descripción
Sumario:A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were synthesized. Among these lactones, lactones 8–12 were new compounds. The cytotoxicity of these synthetic compounds were investigated.

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