Heterochromatin Dynamics during the Differentiation Process Revealed by the DNA Methylation Reporter Mouse, MethylRO

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In mammals, DNA is methylated at CpG sites, which play pivotal roles in gene silencing and chromatin organization. Furthermore, DNA methylation undergoes dynamic changes during development, differentiation, and in pathological processes. The conventional methods represent snapshots; therefore, the d...

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Detalles Bibliográficos
Autores principales: Ueda, Jun, Maehara, Kazumitsu, Mashiko, Daisuke, Ichinose, Takako, Yao, Tatsuma, Hori, Mayuko, Sato, Yuko, Kimura, Hiroshi, Ohkawa, Yasuyuki, Yamagata, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050349/
https://www.ncbi.nlm.nih.gov/pubmed/24936475
http://dx.doi.org/10.1016/j.stemcr.2014.05.008
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