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Human Neural Precursor Cells Promote Neurologic Recovery in a Viral Model of Multiple Sclerosis

Using a viral model of the demyelinating disease multiple sclerosis (MS), we show that intraspinal transplantation of human embryonic stem cell-derived neural precursor cells (hNPCs) results in sustained clinical recovery, although hNPCs were not detectable beyond day 8 posttransplantation. Improved...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Coleman, Ronald, Leang, Ronika, Tran, Ha, Kopf, Alexandra, Walsh, Craig M., Sears-Kraxberger, Ilse, Steward, Oswald, Macklin, Wendy B., Loring, Jeanne F., Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050357/
https://www.ncbi.nlm.nih.gov/pubmed/24936469
http://dx.doi.org/10.1016/j.stemcr.2014.04.005