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Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A(2A) receptor levels in rats subjected to neuroinflammation
BACKGROUND: Acetate supplementation reduces neuroglia activation and pro-inflammatory cytokine expression in rat models of neuroinflammation and Lyme neuroborreliosis. Because single-dose glyceryl triacetate (GTA) treatment increases brain phosphocreatine and reduces brain AMP levels, we postulate t...
Autores principales: | Smith, Mark D, Bhatt, Dhaval P, Geiger, Jonathan D, Rosenberger, Thad A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050445/ https://www.ncbi.nlm.nih.gov/pubmed/24898794 http://dx.doi.org/10.1186/1742-2094-11-99 |
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