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Fine-Tuning of iPSC Derivation by an Inducible Reprogramming System at the Protein Level

Induced pluripotent stem cells (iPSCs) generated from somatic cells by ectopic expression of reprogramming factors, e.g., POU5F1 (OCT4), KLF4, and SOX2, have great potential for regenerative medicine. However, before they can be used in a clinical setting, the mechanism of reprogramming needs to be...

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Detalles Bibliográficos
Autores principales: Sui, Dandan, Sun, Zhaolin, Xu, Chunlong, Wu, Yuanyuan, Capecchi, Mario R., Wu, Sen, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050490/
https://www.ncbi.nlm.nih.gov/pubmed/24936457
http://dx.doi.org/10.1016/j.stemcr.2014.03.013

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