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Systemic Inflammation Impairs Attention and Cognitive Flexibility but Not Associative Learning in Aged Rats: Possible Implications for Delirium
Delirium is a common and morbid condition in elderly hospitalized patients. Its pathophysiology is poorly understood but inflammation has been implicated based on a clinical association with systemic infection and surgery and preclinical data showing that systemic inflammation adversely affects hipp...
Autores principales: | Culley, Deborah J., Snayd, Mary, Baxter, Mark G., Xie, Zhongcong, Lee, In Ho, Rudolph, James, Inouye, Sharon K., Marcantonio, Edward R., Crosby, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050637/ https://www.ncbi.nlm.nih.gov/pubmed/24959140 http://dx.doi.org/10.3389/fnagi.2014.00107 |
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