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Activity of D-amino acid oxidase is widespread in the human central nervous system

It has been proposed that D-amino acid oxidase (DAO) plays an essential role in degrading D-serine, an endogenous coagonist of N-methyl-D-aspartate (NMDA) glutamate receptors. DAO shows genetic association with amyotrophic lateral sclerosis (ALS) and schizophrenia, in whose pathophysiology aberrant...

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Detalles Bibliográficos
Autores principales:	Sasabe, Jumpei, Suzuki, Masataka, Imanishi, Nobuaki, Aiso, Sadakazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050652/ https://www.ncbi.nlm.nih.gov/pubmed/24959138 http://dx.doi.org/10.3389/fnsyn.2014.00014

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