A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

Mammalian development is regulated by the interplay of tissue-specific and ubiquitously expressed transcription factors, such as Sp1. Sp1 knockout mice die in utero with multiple phenotypic aberrations, but the underlying molecular mechanism of this differentiation failure has been elusive. Here, we...

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Detalles Bibliográficos
Autores principales: Gilmour, Jane, Assi, Salam A., Jaegle, Ulrike, Kulu, Divine, van de Werken, Harmen, Clarke, Deborah, Westhead, David R., Philipsen, Sjaak, Bonifer, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050696/
https://www.ncbi.nlm.nih.gov/pubmed/24850855
http://dx.doi.org/10.1242/dev.106054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050696/
https://www.ncbi.nlm.nih.gov/pubmed/24850855
http://dx.doi.org/10.1242/dev.106054

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