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Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites
Meiotic crossovers (COs) are crucial for ensuring accurate homologous chromosome segregation during meiosis I. Because the double-strand breaks (DSBs) that initiate meiotic recombination greatly outnumber eventual COs, this process requires exquisite regulation to narrow down the pool of DSB interme...
Autores principales: | Holloway, J. Kim, Sun, Xianfei, Yokoo, Rayka, Villeneuve, Anne M., Cohen, Paula E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050721/ https://www.ncbi.nlm.nih.gov/pubmed/24891606 http://dx.doi.org/10.1083/jcb.201401122 |
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