Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

Hematological traits are important clinical parameters. To test the role of rare and low-frequency coding variants on hematological traits, we analyzed hemoglobin, hematocrit, white blood cell (WBC) and platelet count in 31,340 individuals genotyped on an exome array. We identified several missense...

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Detalles Bibliográficos
Autores principales: Auer, Paul L., Teumer, Alexander, Schick, Ursula, O’Shaughnessy, Andrew, Lo, Ken Sin, Chami, Nathalie, Carlson, Chris, de Denus, Simon, Dubé, Marie-Pierre, Haessler, Jeff, Jackson, Rebecca D., Kooperberg, Charles, Perreault, Louis-Philippe Lemieux, Nauck, Matthias, Peters, Ulrike, Rioux, John D., Schmidt, Frank, Turcot, Valérie, Völker, Uwe, Völzke, Henry, Greinacher, Andreas, Hsu, Li, Tardif, Jean-Claude, Diaz, George A., Reiner, Alexander P., Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050975/
https://www.ncbi.nlm.nih.gov/pubmed/24777453
http://dx.doi.org/10.1038/ng.2962

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