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9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione

In the title compound, C(33)H(27)BrClNO(4), the di­hydro­pyridine ring adopts a flattened boat conformation. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π inter­actions l...

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Autores principales: Akkurt, Mehmet, Mohamed, Shaaban K., Abdelhamid, Antar A., Gaber, Abdel-Aal M., Albayati, Mustafa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051074/
https://www.ncbi.nlm.nih.gov/pubmed/24940246
http://dx.doi.org/10.1107/S1600536814010460
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author Akkurt, Mehmet
Mohamed, Shaaban K.
Abdelhamid, Antar A.
Gaber, Abdel-Aal M.
Albayati, Mustafa R.
author_facet Akkurt, Mehmet
Mohamed, Shaaban K.
Abdelhamid, Antar A.
Gaber, Abdel-Aal M.
Albayati, Mustafa R.
author_sort Akkurt, Mehmet
collection PubMed
description In the title compound, C(33)H(27)BrClNO(4), the di­hydro­pyridine ring adopts a flattened boat conformation. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π inter­actions link the mol­ecules, forming a three-dimensional network. In the acridinedione ring system, the two ring C atoms at the 2- and 3-positions, and the C atom at the 6-position and the atoms of the phenyl ring attached to the C atom at the 6-position are disordered over two sets of sites with occupancy ratios of 0.783 (5):0.217 (5) and 0.526 (18):0.474 (18), respectively.
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spelling pubmed-40510742014-06-17 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione Akkurt, Mehmet Mohamed, Shaaban K. Abdelhamid, Antar A. Gaber, Abdel-Aal M. Albayati, Mustafa R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(33)H(27)BrClNO(4), the di­hydro­pyridine ring adopts a flattened boat conformation. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π inter­actions link the mol­ecules, forming a three-dimensional network. In the acridinedione ring system, the two ring C atoms at the 2- and 3-positions, and the C atom at the 6-position and the atoms of the phenyl ring attached to the C atom at the 6-position are disordered over two sets of sites with occupancy ratios of 0.783 (5):0.217 (5) and 0.526 (18):0.474 (18), respectively. International Union of Crystallography 2014-05-17 /pmc/articles/PMC4051074/ /pubmed/24940246 http://dx.doi.org/10.1107/S1600536814010460 Text en © Akkurt et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Akkurt, Mehmet
Mohamed, Shaaban K.
Abdelhamid, Antar A.
Gaber, Abdel-Aal M.
Albayati, Mustafa R.
9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title_full 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title_fullStr 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title_full_unstemmed 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title_short 9-(3-Bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2H,5H)-dione
title_sort 9-(3-bromo-5-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­eth­yl)-3,6-diphenyl-3,4,9,10-tetra­hydro­acridine-1,8(2h,5h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051074/
https://www.ncbi.nlm.nih.gov/pubmed/24940246
http://dx.doi.org/10.1107/S1600536814010460
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