Cargando…
9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione
In the title compound, C(33)H(27)BrClNO(4), the dihydropyridine ring adopts a flattened boat conformation. The molecular conformation is stabilized by an intramolecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π interactions l...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051074/ https://www.ncbi.nlm.nih.gov/pubmed/24940246 http://dx.doi.org/10.1107/S1600536814010460 |
_version_ | 1782320053523316736 |
---|---|
author | Akkurt, Mehmet Mohamed, Shaaban K. Abdelhamid, Antar A. Gaber, Abdel-Aal M. Albayati, Mustafa R. |
author_facet | Akkurt, Mehmet Mohamed, Shaaban K. Abdelhamid, Antar A. Gaber, Abdel-Aal M. Albayati, Mustafa R. |
author_sort | Akkurt, Mehmet |
collection | PubMed |
description | In the title compound, C(33)H(27)BrClNO(4), the dihydropyridine ring adopts a flattened boat conformation. The molecular conformation is stabilized by an intramolecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π interactions link the molecules, forming a three-dimensional network. In the acridinedione ring system, the two ring C atoms at the 2- and 3-positions, and the C atom at the 6-position and the atoms of the phenyl ring attached to the C atom at the 6-position are disordered over two sets of sites with occupancy ratios of 0.783 (5):0.217 (5) and 0.526 (18):0.474 (18), respectively. |
format | Online Article Text |
id | pubmed-4051074 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-40510742014-06-17 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione Akkurt, Mehmet Mohamed, Shaaban K. Abdelhamid, Antar A. Gaber, Abdel-Aal M. Albayati, Mustafa R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(33)H(27)BrClNO(4), the dihydropyridine ring adopts a flattened boat conformation. The molecular conformation is stabilized by an intramolecular O—H⋯O hydrogen bond, with an S(8) ring motif. In the crystal, O—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds, and C—H⋯π interactions link the molecules, forming a three-dimensional network. In the acridinedione ring system, the two ring C atoms at the 2- and 3-positions, and the C atom at the 6-position and the atoms of the phenyl ring attached to the C atom at the 6-position are disordered over two sets of sites with occupancy ratios of 0.783 (5):0.217 (5) and 0.526 (18):0.474 (18), respectively. International Union of Crystallography 2014-05-17 /pmc/articles/PMC4051074/ /pubmed/24940246 http://dx.doi.org/10.1107/S1600536814010460 Text en © Akkurt et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Akkurt, Mehmet Mohamed, Shaaban K. Abdelhamid, Antar A. Gaber, Abdel-Aal M. Albayati, Mustafa R. 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title | 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title_full | 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title_fullStr | 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title_full_unstemmed | 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title_short | 9-(3-Bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2H,5H)-dione |
title_sort | 9-(3-bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,9,10-tetrahydroacridine-1,8(2h,5h)-dione |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051074/ https://www.ncbi.nlm.nih.gov/pubmed/24940246 http://dx.doi.org/10.1107/S1600536814010460 |
work_keys_str_mv | AT akkurtmehmet 93bromo5chloro2hydroxyphenyl102hydroxyethyl36diphenyl34910tetrahydroacridine182h5hdione AT mohamedshaabank 93bromo5chloro2hydroxyphenyl102hydroxyethyl36diphenyl34910tetrahydroacridine182h5hdione AT abdelhamidantara 93bromo5chloro2hydroxyphenyl102hydroxyethyl36diphenyl34910tetrahydroacridine182h5hdione AT gaberabdelaalm 93bromo5chloro2hydroxyphenyl102hydroxyethyl36diphenyl34910tetrahydroacridine182h5hdione AT albayatimustafar 93bromo5chloro2hydroxyphenyl102hydroxyethyl36diphenyl34910tetrahydroacridine182h5hdione |