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N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide

The title compound, C(12)H(17)N(3)OS, crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angle between the mean planes of the benzene ring and the hydrazinecarbo­thio­amide group are 6.9 (4) and 37.2 (5)° in mol­ecules A and B, respectively. An intra­molecula...

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Detalles Bibliográficos
Autores principales: Anderson, Brian J., Hall, Jeffrey R., Jasinski, Jerry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051077/
https://www.ncbi.nlm.nih.gov/pubmed/24940300
http://dx.doi.org/10.1107/S1600536814012203
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author Anderson, Brian J.
Hall, Jeffrey R.
Jasinski, Jerry P.
author_facet Anderson, Brian J.
Hall, Jeffrey R.
Jasinski, Jerry P.
author_sort Anderson, Brian J.
collection PubMed
description The title compound, C(12)H(17)N(3)OS, crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angle between the mean planes of the benzene ring and the hydrazinecarbo­thio­amide group are 6.9 (4) and 37.2 (5)° in mol­ecules A and B, respectively. An intra­molecular O—H⋯N hydrogen bond is observed in each mol­ecule. This serves to maintain an approximately planar conformation for mol­ecule A, but leaves a significant twist between these two groups in mol­ecule B. In the crystal, a weak N—H⋯S inter­action is observed, forming inversion dimers among the B mol­ecules and resulting in an R (2) (2)(8) motif. These dimers are further inter­connected by weak N—H⋯O and C—H⋯O inter­molecular inter­actions, forming chains along [011].
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spelling pubmed-40510772014-06-17 N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide Anderson, Brian J. Hall, Jeffrey R. Jasinski, Jerry P. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(12)H(17)N(3)OS, crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angle between the mean planes of the benzene ring and the hydrazinecarbo­thio­amide group are 6.9 (4) and 37.2 (5)° in mol­ecules A and B, respectively. An intra­molecular O—H⋯N hydrogen bond is observed in each mol­ecule. This serves to maintain an approximately planar conformation for mol­ecule A, but leaves a significant twist between these two groups in mol­ecule B. In the crystal, a weak N—H⋯S inter­action is observed, forming inversion dimers among the B mol­ecules and resulting in an R (2) (2)(8) motif. These dimers are further inter­connected by weak N—H⋯O and C—H⋯O inter­molecular inter­actions, forming chains along [011]. International Union of Crystallography 2014-05-31 /pmc/articles/PMC4051077/ /pubmed/24940300 http://dx.doi.org/10.1107/S1600536814012203 Text en © Anderson et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Anderson, Brian J.
Hall, Jeffrey R.
Jasinski, Jerry P.
N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title_full N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title_fullStr N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title_full_unstemmed N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title_short N-Ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
title_sort n-ethyl-2-[1-(2-hy­droxy-4-methyl­phen­yl)ethyl­idene]hydrazinecarbo­thio­amide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051077/
https://www.ncbi.nlm.nih.gov/pubmed/24940300
http://dx.doi.org/10.1107/S1600536814012203
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