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Coupled ion binding and structural transitions along the transport cycle of glutamate transporters
Membrane transporters that clear the neurotransmitter glutamate from synapses are driven by symport of sodium ions and counter-transport of a potassium ion. Previous crystal structures of a homologous archaeal sodium and aspartate symporter showed that a dedicated transport domain carries the substr...
Autores principales: | Verdon, Grégory, Oh, SeCheol, Serio, Ryan N, Boudker, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051121/ https://www.ncbi.nlm.nih.gov/pubmed/24842876 http://dx.doi.org/10.7554/eLife.02283 |
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