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Coupled ion binding and structural transitions along the transport cycle of glutamate transporters

Membrane transporters that clear the neurotransmitter glutamate from synapses are driven by symport of sodium ions and counter-transport of a potassium ion. Previous crystal structures of a homologous archaeal sodium and aspartate symporter showed that a dedicated transport domain carries the substr...

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Detalles Bibliográficos
Autores principales: Verdon, Grégory, Oh, SeCheol, Serio, Ryan N, Boudker, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051121/
https://www.ncbi.nlm.nih.gov/pubmed/24842876
http://dx.doi.org/10.7554/eLife.02283

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