Cargando…

Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review

BACKGROUND: KRAS mutations in codons 12 and 13 are established predictive biomarkers for anti-EGFR therapy in colorectal cancer. Previous studies suggest that KRAS codon 61 and 146 mutations may also predict resistance to anti-EGFR therapy in colorectal cancer. However, clinicopathological, molecula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Imamura, Yu, Lochhead, Paul, Yamauchi, Mai, Kuchiba, Aya, Qian, Zhi Rong, Liao, Xiaoyun, Nishihara, Reiko, Jung, Seungyoun, Wu, Kana, Nosho, Katsuhiko, Wang, Yaoyu E, Peng, Shouyong, Bass, Adam J, Haigis, Kevin M, Meyerhardt, Jeffrey A, Chan, Andrew T, Fuchs, Charles S, Ogino, Shuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051153/ https://www.ncbi.nlm.nih.gov/pubmed/24885062 http://dx.doi.org/10.1186/1476-4598-13-135

Ejemplares similares

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
por: Loupakis, F, et al.
Publicado: (2009)

Simultaneous identification of 36 mutations in KRAS codons 61and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit
por: Bando, Hideaki, et al.
Publicado: (2013)

Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines
por: Varshavi, Dorna, et al.
Publicado: (2020)

Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value
por: Ahn, Hong-Min, et al.
Publicado: (2023)

High Frequency of KRAS Codon 146 and FBXW7 Mutations in Thai Patients with Stage II-III Colon Cancer
por: Korphaisarn, Krittiya, et al.
Publicado: (2019)

Measurement of average decoding rates of the 61 sense codons in vivo
por: Gardin, Justin, et al.
Publicado: (2014)

Identification of Codon 146 KRAS Variants in Isolated Epidermal Nevus and Multiple Lesions in Oculoectodermal Syndrome: Confirmation of the Phenotypic Continuum of Mosaic RASopathies
por: Beyens, Aude, et al.
Publicado: (2022)

TGFBR2 and BAX Mononucleotide Tract Mutations, Microsatellite Instability, and Prognosis in 1072 Colorectal Cancers
por: Shima, Kaori, et al.
Publicado: (2011)

KRAS Codon 12 and 13 Mutations in Gastric Cancer in the Northeast Iran
por: Ayatollahi, Hossein, et al.
Publicado: (2018)

Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines
por: Stolze, Britta, et al.
Publicado: (2015)

Codon usage and codon context bias in Xanthophyllomyces dendrorhous
por: Baeza, Marcelo, et al.
Publicado: (2015)

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance
por: Ali, Moiez, et al.
Publicado: (2017)

KRAS exon 2 codon 13 mutation is associated with a better prognosis than codon 12 mutation following lung metastasectomy in colorectal cancer
por: Renaud, Stéphane, et al.
Publicado: (2016)

Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma
por: Lee, Sung, et al.
Publicado: (2011)

Polymorphisms of Codons 110, 146, 211 and 222 at the Goat PRNP Locus and Their Association with Scrapie in Greece
por: Gelasakis, Athanasios I., et al.
Publicado: (2021)

Codon Adaptation Index as a measure of dominating codon bias
por: Carbone, A, et al.
Publicado: (2002)

The Dynamic Codon Biaser: calculating prokaryotic codon usage biases
por: Dehlinger, Brian, et al.
Publicado: (2021)

iCodon customizes gene expression based on the codon composition
por: Diez, Michay, et al.
Publicado: (2022)

The Codon Statistics Database: A Database of Codon Usage Bias
por: Subramanian, Krishnamurthy, et al.
Publicado: (2022)

Multiple Congenital Melanocytic Nevi and Neurocutaneous Melanosis Are Caused by Postzygotic Mutations in Codon 61 of NRAS
por: Kinsler, Veronica A, et al.
Publicado: (2013)

Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages
por: Li, Wenbin, et al.
Publicado: (2015)

CodonO: codon usage bias analysis within and across genomes
por: Angellotti, Michael C., et al.
Publicado: (2007)

CodonLogo: a sequence logo-based viewer for codon patterns
por: Sharma, Virag, et al.
Publicado: (2012)

Modal Codon Usage: Assessing the Typical Codon Usage of a Genome
por: Davis, James J., et al.
Publicado: (2010)

Discrepancy among the synonymous codons with respect to their selection as optimal codon in bacteria
por: Satapathy, Siddhartha Sankar, et al.
Publicado: (2016)

Selection for tandem stop codons in ciliate species with reassigned stop codons
por: Fleming, Ira, et al.
Publicado: (2019)

Analysis of computational codon usage models and their association with translationally slow codons
por: Wright, Gabriel, et al.
Publicado: (2020)

Cryptosporidium felis differs from other Cryptosporidium spp. in codon usage
por: Li, Jiayu, et al.
Publicado: (2021)

Rare Codons Cluster
por: Clarke, Thomas F., et al.
Publicado: (2008)

Codon optimality in cancer
por: Gillen, Sarah L., et al.
Publicado: (2021)

Codon usage bias
por: Parvathy, Sujatha Thankeswaran, et al.
Publicado: (2021)

Expanding codon size
por: Siddika, Tarana, et al.
Publicado: (2022)

Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer
por: van de Haar, Joris, et al.
Publicado: (2023)

Efficient expression of gene variants that harbour AGA codons next to the initiation codon
por: Zamora-Romo, Efraín, et al.
Publicado: (2007)

Relative Codon Adaptation Index, a Sensitive Measure of Codon Usage Bias
por: Lee, Soohyun, et al.
Publicado: (2010)

Computational identification of rare codons of Escherichia coli based on codon pairs preference
por: Wu, Xianming, et al.
Publicado: (2010)

Modifying the genetic code: Converting nonsense codons into sense codons by targeted pseudouridylation
por: Karijolich, John, et al.
Publicado: (2011)

Evidence that Natural Selection on Codon Usage in Drosophila pseudoobscura Varies Across Codons
por: Kliman, Richard M.
Publicado: (2014)

Codon-by-Codon Modulation of Translational Speed and Accuracy Via mRNA Folding
por: Yang, Jian-Rong, et al.
Publicado: (2014)

Modelling the Efficiency of Codon–tRNA Interactions Based on Codon Usage Bias
por: Sabi, Renana, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_c337o36o5f1p0bk2uja997117n