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Reprogramming the Methylome: Erasing Memory and Creating Diversity
The inheritance of epigenetic marks, in particular DNA methylation, provides a molecular memory that ensures faithful commitment to transcriptional programs during mammalian development. Epigenetic reprogramming results in global hypomethylation of the genome together with a profound loss of memory,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051243/ https://www.ncbi.nlm.nih.gov/pubmed/24905162 http://dx.doi.org/10.1016/j.stem.2014.05.008 |