A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses

Vaccine development and pathogenesis studies for human enterovirus 71 are limited by a lack of suitable animal models. Here, we report the development of a novel neonatal gnotobiotic pig model using the non-pig-adapted neurovirulent human enterovirus 71 strain BJ110, which has a C4 genotype. Porcine...

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Detalles Bibliográficos
Autores principales: Yang, Xingdong, Li, Guohua, Wen, Ke, Bui, Tammy, Liu, Fangning, Kocher, Jacob, Jortner, Bernard S, Vonck, Marlice, Pelzer, Kevin, Deng, Jie, Zhu, Runan, Li, Yuyun, Qian, Yuan, Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051366/
https://www.ncbi.nlm.nih.gov/pubmed/26038741
http://dx.doi.org/10.1038/emi.2014.35

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