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Impact of Ketamine on Learning and Memory Function, Neuronal Apoptosis and Its Potential Association with miR-214 and PTEN in Adolescent Rats

Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is used as a general pediatric anesthetic and anti-depressive drug. Recent studies suggest that ketamine enhances neuronal apoptosis in developing rats. The goal of this study is to explore whether ketamine could result in learning and me...

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Detalles Bibliográficos
Autores principales: Wang, Ji, Zhou, Min, Wang, Xiaobin, Yang, Xiaoling, Wang, Maohua, Zhang, Chunxiang, Zhou, Shuzhi, Tang, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051782/
https://www.ncbi.nlm.nih.gov/pubmed/24914689
http://dx.doi.org/10.1371/journal.pone.0099855