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Impact of Ketamine on Learning and Memory Function, Neuronal Apoptosis and Its Potential Association with miR-214 and PTEN in Adolescent Rats
Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is used as a general pediatric anesthetic and anti-depressive drug. Recent studies suggest that ketamine enhances neuronal apoptosis in developing rats. The goal of this study is to explore whether ketamine could result in learning and me...
Autores principales: | Wang, Ji, Zhou, Min, Wang, Xiaobin, Yang, Xiaoling, Wang, Maohua, Zhang, Chunxiang, Zhou, Shuzhi, Tang, Ni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051782/ https://www.ncbi.nlm.nih.gov/pubmed/24914689 http://dx.doi.org/10.1371/journal.pone.0099855 |
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