The potential clinical applications and prospects of microRNAs in lung cancer

Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Gao, Fei, Ma, Jin-lu, Sun, Wen-ze, Song, Li-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051813/
https://www.ncbi.nlm.nih.gov/pubmed/24940074
http://dx.doi.org/10.2147/OTT.S62227
Descripción
Sumario:Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.

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