The potential clinical applications and prospects of microRNAs in lung cancer

Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost...

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Autores principales: Gao, Ying, Gao, Fei, Ma, Jin-lu, Sun, Wen-ze, Song, Li-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051813/
https://www.ncbi.nlm.nih.gov/pubmed/24940074
http://dx.doi.org/10.2147/OTT.S62227
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author Gao, Ying
Gao, Fei
Ma, Jin-lu
Sun, Wen-ze
Song, Li-ping
author_facet Gao, Ying
Gao, Fei
Ma, Jin-lu
Sun, Wen-ze
Song, Li-ping
author_sort Gao, Ying
collection PubMed
description Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.
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spelling pubmed-40518132014-06-17 The potential clinical applications and prospects of microRNAs in lung cancer Gao, Ying Gao, Fei Ma, Jin-lu Sun, Wen-ze Song, Li-ping Onco Targets Ther Review Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers. Dove Medical Press 2014-06-04 /pmc/articles/PMC4051813/ /pubmed/24940074 http://dx.doi.org/10.2147/OTT.S62227 Text en © 2014 Gao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Gao, Ying
Gao, Fei
Ma, Jin-lu
Sun, Wen-ze
Song, Li-ping
The potential clinical applications and prospects of microRNAs in lung cancer
title The potential clinical applications and prospects of microRNAs in lung cancer
title_full The potential clinical applications and prospects of microRNAs in lung cancer
title_fullStr The potential clinical applications and prospects of microRNAs in lung cancer
title_full_unstemmed The potential clinical applications and prospects of microRNAs in lung cancer
title_short The potential clinical applications and prospects of microRNAs in lung cancer
title_sort potential clinical applications and prospects of micrornas in lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051813/
https://www.ncbi.nlm.nih.gov/pubmed/24940074
http://dx.doi.org/10.2147/OTT.S62227
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