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Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment

The presence of abnormal cells with malignant potential or neoplastic characteristics is a relatively common phenomenon. The interaction of these abnormal cells with their microenvironment is essential for tumor development, protection from the body’s immune or defence mechanisms, later progression...

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Detalles Bibliográficos
Autores principales: Goubran, Hadi A, Kotb, Rami R, Stakiw, Julie, Emara, Mohamed E, Burnouf, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051818/
https://www.ncbi.nlm.nih.gov/pubmed/24926201
http://dx.doi.org/10.4137/CGM.S11285
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author Goubran, Hadi A
Kotb, Rami R
Stakiw, Julie
Emara, Mohamed E
Burnouf, Thierry
author_facet Goubran, Hadi A
Kotb, Rami R
Stakiw, Julie
Emara, Mohamed E
Burnouf, Thierry
author_sort Goubran, Hadi A
collection PubMed
description The presence of abnormal cells with malignant potential or neoplastic characteristics is a relatively common phenomenon. The interaction of these abnormal cells with their microenvironment is essential for tumor development, protection from the body’s immune or defence mechanisms, later progression and the development of life-threatening or metastatic disease. The tumor microenvironment is a collective term that includes the tumor’s surrounding and supportive stroma, the different effectors of the immune system, blood platelets, hormones and other humoral factors. A better understanding of the interplay between the tumor cells and its microenvironment can provide efficient tools for cancer management, as well as better prevention, screening and risk assessment protocols.
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spelling pubmed-40518182014-06-12 Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment Goubran, Hadi A Kotb, Rami R Stakiw, Julie Emara, Mohamed E Burnouf, Thierry Cancer Growth Metastasis Review The presence of abnormal cells with malignant potential or neoplastic characteristics is a relatively common phenomenon. The interaction of these abnormal cells with their microenvironment is essential for tumor development, protection from the body’s immune or defence mechanisms, later progression and the development of life-threatening or metastatic disease. The tumor microenvironment is a collective term that includes the tumor’s surrounding and supportive stroma, the different effectors of the immune system, blood platelets, hormones and other humoral factors. A better understanding of the interplay between the tumor cells and its microenvironment can provide efficient tools for cancer management, as well as better prevention, screening and risk assessment protocols. Libertas Academica 2014-06-02 /pmc/articles/PMC4051818/ /pubmed/24926201 http://dx.doi.org/10.4137/CGM.S11285 Text en © 2014 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Review
Goubran, Hadi A
Kotb, Rami R
Stakiw, Julie
Emara, Mohamed E
Burnouf, Thierry
Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title_full Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title_fullStr Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title_full_unstemmed Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title_short Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
title_sort regulation of tumor growth and metastasis: the role of tumor microenvironment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051818/
https://www.ncbi.nlm.nih.gov/pubmed/24926201
http://dx.doi.org/10.4137/CGM.S11285
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