Altered Proteolysis in Fibroblasts of Alzheimer Patients with Predictive Implications for Subjects at Risk of Disease

There is great interest in developing reliable biomarkers to support antemortem diagnosis of late-onset Alzheimer's disease (AD). Early prediction and diagnosis of AD might be improved by the detection of a proteolytic dysfunction in extracts from cultured AD fibroblasts, producing altered isoe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mocali, Alessandra, Della Malva, Nunzia, Abete, Claudia, Mitidieri Costanza, Vito Antonio, Bavazzano, Antonio, Boddi, Vieri, Sanchez, Luis, Dessì, Sandra, Pani, Alessandra, Paoletti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052202/
https://www.ncbi.nlm.nih.gov/pubmed/24949214
http://dx.doi.org/10.1155/2014/520152

Ejemplares similares

Ejemplares similares