Cargando…
Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells
BACKGROUND: Insulin-like growth factor I (IGF-I) can induce epithelial mesenchymal transition (EMT) in many epithelial tumors; however, the molecular mechanism by which this occurs is not clearly understood. Additionally, little is known about the involvement of IGF-I in gastric cancer. METHODS: Two...
Autores principales: | Li, Heming, Xu, Ling, Li, Ce, Zhao, Lei, Ma, Yanju, Zheng, Huachuan, Li, Zhi, Zhang, Ye, Wang, Ruoyu, Liu, Yunpeng, Qu, Xiujuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052283/ https://www.ncbi.nlm.nih.gov/pubmed/24885194 http://dx.doi.org/10.1186/1476-4598-13-136 |
Ejemplares similares
-
The E3 ubiquitin ligase Cbl-b improves the prognosis of RANK positive breast cancer patients by inhibiting RANKL-induced cell migration and metastasis
por: Zhang, Lingyun, et al.
Publicado: (2015) -
The E3 Ubiquitin Ligase Cbl-b Predicts Favorable Prognosis in Breast Cancer
por: Liu, Xiuming, et al.
Publicado: (2020) -
E3 Ubiquitin Ligase Cbl-b Prevents Tumor Metastasis by Maintaining the Epithelial Phenotype in Multiple Drug-Resistant Gastric and Breast Cancer Cells()
por: Xu, Ling, et al.
Publicado: (2017) -
Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells
por: Tong, Haijun, et al.
Publicado: (2021) -
IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights
por: Li, Heming, et al.
Publicado: (2017)