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Investigating perturbed pathway modules from gene expression data via structural equation models
BACKGROUND: It is currently accepted that the perturbation of complex intracellular networks, rather than the dysregulation of a single gene, is the basis for phenotypical diversity. High-throughput gene expression data allow to investigate changes in gene expression profiles among different conditi...
Autores principales: | Pepe, Daniele, Grassi, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052286/ https://www.ncbi.nlm.nih.gov/pubmed/24885496 http://dx.doi.org/10.1186/1471-2105-15-132 |
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