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Investigating perturbed pathway modules from gene expression data via structural equation models

BACKGROUND: It is currently accepted that the perturbation of complex intracellular networks, rather than the dysregulation of a single gene, is the basis for phenotypical diversity. High-throughput gene expression data allow to investigate changes in gene expression profiles among different conditi...

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Detalles Bibliográficos
Autores principales:	Pepe, Daniele, Grassi, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052286/ https://www.ncbi.nlm.nih.gov/pubmed/24885496 http://dx.doi.org/10.1186/1471-2105-15-132

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